Searching using MeSH terms allows for terms to be searched as a Major Concept (the search will return only records for which the subject heading is a major point of the article) and also provides the ability to Explode (expands the subject heading to retrieve all references indexed to that term, plus any narrower terms that are connected). For example, articles which talk about cancer, tumours or leukaemia will be mapped to the Medical Subject Heading [MESH] term Neoplasms. A worked example of MeSH in action is demonstrated by PubMed.
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